Purifying and Concentrating Imiquimod and Metabolites from Large Volumes of Urine 05 Apr 2010: This application note demonstrates the use of large diameter (47 mm) Empore Extraction Disks to purify and concentrate a novel immunomodulator drug, Imiquimod (AldaraTM), and its metabolites from urine. The eluates were analyzed by different chromatographic techniques (HPLC and TLC) to determine the nature and number of metabolites present. 3M Bioanalytical
